乙醇酸甲酯合成工艺的研究及应用进展
Research and application progress on synthesis process of methyl glycolate
- 低碳化学与化工 2024, 49(1): 60-69.
- 作者机构：
中石化（大连）石油化工研究院有限公司，辽宁 大连 116045
- 作者简介：
李秀峥（1990—），硕士，助理研究员，研究方向为可降解材料单体、生物基材料研发，E-mail：lixiuzheng.fshy@sinopec.com。
白富栋（1981—），博士，高级工程师，研究方向为可降解材料单体、生物基材料研发，E-mail：baifudong.fshy@sinopec.com。
- 基金信息：
DOI：10.12434/j.issn.2097-2547.20230093
中图分类号：
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李秀峥,白富栋,张雷等.乙醇酸甲酯合成工艺的研究及应用进展[J].低碳化学与化工,2024,49(01):60-69.
LI Xiuzheng,BAI Fudong,ZHANG Lei,et al.Research and application progress on synthesis process of methyl glycolate[J].Low-carbon Chemistry and Chemical Engineering,2024,49(01):60-69.
李秀峥,白富栋,张雷等.乙醇酸甲酯合成工艺的研究及应用进展[J].低碳化学与化工,2024,49(01):60-69. DOI： 10.12434/j.issn.2097-2547.20230093.
LI Xiuzheng,BAI Fudong,ZHANG Lei,et al.Research and application progress on synthesis process of methyl glycolate[J].Low-carbon Chemistry and Chemical Engineering,2024,49(01):60-69. DOI： 10.12434/j.issn.2097-2547.20230093.
摘要
乙醇酸甲酯是一种重要的化工原料，研究乙醇酸甲酯合成工艺具有重要意义。介绍了乙醇酸甲酯的合成工艺，分别为氯乙酸水解法、甲酸甲酯与甲醛偶联法、甲醛羰化酯化法、草酸二甲酯加氢还原法、乙二醇与甲醇合成法、生物质转化法、甲缩醛与甲酸自由基偶联法、甲醛与氢氰酸加成法及乙二醛与甲醇一步合成法，对比了各工艺的优缺点，指出了乙醇酸甲酯在可降解塑料、食品、药品、农药及化工领域的用途，分析了乙醇酸甲酯生产工艺研究进展，最后对乙醇酸甲酯合成工艺进行了总结及展望。传统的乙醇酸甲酯生产工艺存在较多问题，且难以大规模生产。采用草酸二甲酯加氢还原法合成乙醇酸甲酯，然后制备乙交酯及聚乙醇酸的路线在中国具有广阔的发展前景，在解决全流程中存在的问题后，有望实现大规模工业化生产。生物质转化法以可再生的纤维素等资源为原料合成乙醇酸甲酯，具有绿色低碳的优点，有助于实现双碳目标。
Abstract
Methyl glycolate is an important chemical raw material, so it is of great significance to study the synthesis process of methyl glycolate. The synthesis process of methyl glycolate was introduced, including chloroacetic acid hydrolysis method, methyl formate and formaldehyde coupling method, formaldehyde carbonylation esterification method, dimethyl oxalate hydrogenation reduction method, synthesis of ethylene glycol and methanol, biomass conversion method, methylal and formic acid free radical coupling method, formaldehyde and hydrocyanic acid addition method and one-step synthesis of glyoxal and methanol method. The advantages and disadvantages of each process were analyzed. The application of methyl glycolate in the fields of degradable plastic, food, medicine, pesticide and chemical industry was pointed out. The research progress of methyl glycolate production technology was analyzed. Finally, the synthesis process of methyl glycolate was summarized and prospected. There are many problems in the traditional production process of methyl glycolate, and it is difficult to produce on a large scale. The dimethyl oxalate hydrogenation reduction method to synthesize methyl glycolate and then to synthesize ethyl ester and polyglycolic acid has broad development prospects in China. After solving the problems existing in the whole process, large-scale industrial production will be realized. Biomass conversion process uses renewable cellulose and other resources as raw materials to produce methyl glycolate, which has the advantages of green and low-carbon, and helps to achieve Double Carbon goals.
关键词
乙醇酸甲酯合成工艺草酸二甲酯聚乙醇酸
Keywords
methyl glycolatesynthesis processdimethyl oxalatepolyglycolic acid
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