Direct synthesis of dimethyl carbonate（DMC） from carbon dioxide（CO,2,） and methanol（CH,3,OH） can yield chemicals with high added value and mitigate the greenhouse effect.Due to thermodynamic limitations,the equilibrium conversion rate of this reaction is low.The introduction of 2-cyanopyridine as the dehydrating agent can make the reaction proceed in the direction of DMC to a greater extent.In-doped CeO,2, catalyst（In,x,CeO,2,x is the mole ratio of In to Ce） was prepared by coprecipitation method,and the effect of In doping on the catalytic activity of CO,2, and methanol synthesis of DMC was investigated.The catalytic activity evaluation results show that the time and space yield of In,0.01,CeO,2, catalyst prepared by coprecipitation method is 88.81 mmol/（g·h）（the yield of DMC catalyzed by 1 g catalyst within 1 h is 88.81 mmol,the same as below）,which is higher than that of CeO,2, catalyst（49.83 mmol/g·h）.The crystal structure,specific surface area and surface composition of the catalyst were analyzed by XRD,BET and XPS.The characterization analysis confirmed that In doping into CeO,2, lattice significantly increased the relative content of oxygen vacancies on the catalytic surface,resulting in an increase in the number of oxygen vacancies,which was conducive to the improvement of catalytic activity.When x is greater than 0.01,excess In will adhere to the surface of the catalyst and block the pore channel,resulting in the reduction of CeO,2, content on the surface and specific surface area of the catalyst,and thus resulting in the reduction of the number of oxygen vacancies,and thus the catalytic activity of the catalyst.