The mixture of isopropanol-water was separated with ethylene glycol as the extractant.With the goal of energy reduction,cost saving and CO,2, emissions reduction,heat pump and heat integration technology were used to strengthen the extractive distillation process.Using Aspen Plus software,the conventional extractive distillation,the heat pump extractive distillation and the heat integrated-heat pump extractive distillation were simulated.The above processes were evaluated and compared from the energy consumption,total annual cost（TAC） and CO,2, emissions.Under the same design basis and requirements,the results show that heat pump technology with compressor performance coefficient of 10.19 can significantly reduce energy consumption.Compared with the conventional extractive distillation,the heat pump extractive distillation scheme 2 can save energy by 28%,reduce CO,2, emissions by 3.746×10~6 kg/a and reduce TAC by 0.72×10~5 USD when the payback period is 3 a.The heat integrated-heat pump extractive distillation which make full use of the sensible heat of circulating extractant has more advantages.It can save energy by 35%,reduce CO,2, emissions by 8.457×10~6 kg/a and reduce TAC by 1.70×10~5 USD,has better environmental and economic benefits.